Overview
• Detection method - Fluorescence Microscopy
• Applications:
• Visualize nuclear translocation and activation of p53 protein in mammalian cells.
• Detection of increased cellular stress or DNA damage.
• Screening for potential inhibitors that disrupt the interaction between p53 and MDM2
AffiASSAY® p53 Nuclear Translocation Assay Kit (Cell-Based)
• Simple procedure to visualize p53 nuclear translocation in ~ 3 hours
• Fast and contains Nutlin-3 that serves as a control to induce p53 translocation from the cytoplasm to the nucleus.
Alternative Name
N/A
Species Reactivity
Mammalian
Applications
Visualize nuclear translocation and activation of p53 protein in mammalian cells.
Tag Line
N/A
Detection Method
Fluorescence (Ex/Em = 360/460 nm)
Sample Type
Adherent or suspension human cells
Storage Conditions
-20°C
Shipping Conditions
Gel Pack
Shelf life
12 Months